Split into 12 sections, the full resource consists of over 300 fully searchable guidelines designed to assist the clinician in selecting the most appropriate investigation for a given diagnostic or imaging problem:

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Each section sets out the clinical scenario, including red flags, and lists relevant procedures with an indication of the associated radiation dose. For each procedure, there is a recommendation on its appropriateness (together with the grade). Finally, an explanatory comment is included when required to clarify the circumstances in which the procedure should be used. 

The recommendations used are: 
1.Indicated. Investigations most likely to contribute to the clinical diagnosis and management.
2.Specialised investigation. Specialised investigations are frequently complex, time-consuming and/or resource intensive,and will usually only be undertaken after discussion with the radiologist or according to locally agreed protocols.
3.Indicated only in specific circumstances. Non-routine investigations, usually only undertaken if a clinician provides cogent reasons or if the radiologist believes the examination represents an appropriate means of furthering the diagnosis and management of the patient. With certain clinical problems which may resolve with time, it may be correct to defer investigation.
4.Not indicated. Investigations for which the proposed rationale is no longer appropriate.
All guidelines have been reviewed by expert panels comprising specialist UK radiologists.
The process was accredited by NHS Evidence in July 2010.

The guidelines cover all imaging techniques, including:
  • Computed tomography (CT)
  • Interventional radiology (including angiography and minimal access therapy)
  • Magnetic resonance imaging (MRI)
  • Nuclear medicine (NM) and radionuclide imaging
  • PET-CT
  • Ultrasound (US)
  • Radiography and fluoroscopy
  • Contrast agents.